Coding

Part:BBa_K3071005

Designed by: Leung Hei Man   Group: iGEM19_Hong_Kong-CUHK   (2019-10-07)


C reactive protein-like protein (Clp) from Xanthomonas campestris pv. Musacearum

C reactive protein-like protein (Clp) is a global transcriptional regulator that regulates virulence factors production by activating or repressing the expression of a large set of genes in the diffusible signal factor DSF pathway. It regulate the genes that involve in extracellular polysaccharide (EPS) synthesis, flagellum synthesis, protein and fatty acid metabolism, multidrug resistance, iron uptake. They also regulate genes that encoding extracellular enzymes, membrane components, and a few transcription factors.

Allosterically inhibited by cyclic di-GMP (c-di-GMP), which binds to Clp and abolishes its ability to bind its target gene promoter.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 70
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None